Aim:Gouty arthritis is the most common inflammatory arthritis characterized by high serum uric acid levels (hyperuricemia), recurrent arthritis attacks and accumulation of monosodium urate crystals in tissues.The aim of our study is to examine the differences in clinical and demographic features according to gender in patients diagnosed with gouty arthritis. Material and Methods:Gout patients who met the ACR acute gouty arthritis classification criteria were included in our study. Age, gender,smoking,alcohol use,body mass index,concomitant diseases and medications used, pain scores according to visual pain score, and number of attacks per year were recorded.In addition,complete blood count,biochemistry data,erythrocyte sedimentation rates and c-reactive protein levels were recorded. Results: 30 patients were female and 70 were male with an average age. Gout severity assessment scale (GAS) was negatively correlated with gender (r= – 0,202; p= 0,047), and directely with gVAS (r=0,927; p= 0,000) and with erythrocyte sedimentation rate (ESR) (r=0,243; p= 0,025). GAS was correlated with ESR (β = 0,090; p= 0,020) and gVAS (β = 0,922; p= 0,000) in a subsequent stepwise multivariate analysis Conclusion: In our retrospective, database-based, single centre cohort study, GAS was higher in female than in male patients. However, a worse perception of pain by female patients seemed a conditioning factor.
Key words: gouty arthritis, gender, clinic,disease severity, difference
